Preheat your oven to 375°F (190°C).
In a large bowl, combine the softened cream cheese and breakfast sausage.
Add the drained Rotel tomatoes and mix until well combined.
Stir in the shredded cheddar cheese.
In a separate bowl, mix the biscuit mix, garlic powder, onion powder, and black pepper.
Gradually add the dry mixture to the sausage mixture, stirring until fully combined.
Using your hands, form the mixture into small balls (about 1 inch in diameter).
Place the sausage balls on a baking sheet lined with parchment paper.
Bake in the preheated oven for 20-25 minutes, or until golden brown.
Remove from the oven and let cool slightly before serving.