Preheat your oven to 350°F (175°C).
In a large bowl, combine the sausage and Bisquick mix.
Add the shredded cheddar cheese, milk, garlic powder, and onion powder.
Mix the ingredients until fully combined.
Form the mixture into 1-inch balls and place them on a baking sheet.
Arrange the sausage balls about an inch apart on the sheet.
Bake in the preheated oven for 20 minutes or until golden brown.
Remove from oven and let cool for a few minutes.
Serve warm as an appetizer or snack.
Enjoy your delicious Bisquick sausage balls!