Preheat your oven to 350°F (175°C).
In a bowl, mix graham cracker crumbs and melted butter until combined.
Press the mixture firmly into the bottom of a 9-inch springform pan.
Bake the crust for 10 minutes, then let it cool.
In a large mixing bowl, beat the cream cheese until smooth.
Add the peanut butter, powdered sugar, and vanilla extract; mix until well combined.
Add eggs, one at a time, mixing after each addition until just combined.
Pour the cheesecake batter over the cooled crust.
Bake for 50-60 minutes until the center is set but still slightly jiggly.
Let it cool at room temperature, then chill in the refrigerator for at least 4 hours before serving.