Preheat your oven to 350°F (175°C) and grease a 9x5 inch loaf pan.
In a large bowl, cream together the butter and sugar until light and fluffy.
Beat in the eggs, one at a time, mixing well after each addition.
Stir in the lemon zest and juice.
In another bowl, whisk together the flour, baking powder, baking soda, and salt.
Gradually add the dry ingredients to the butter mixture, alternating with buttermilk.
Gently fold in the blueberries.
Pour the batter into the prepared loaf pan.
Bake for 50-60 minutes or until a toothpick inserted comes out clean.
Let cool in the pan for a few minutes before transferring to a wire rack.