Rinse the chicken wings under cold water and pat them dry.

In a bowl, combine the wings with buttermilk and let marinate for at least 30 minutes.

In another bowl, mix flour, garlic powder, onion powder, paprika, salt, and pepper.

Heat vegetable oil in a deep fryer or pot to 350°F (175°C).

Remove wings from buttermilk and dredge in the flour mixture.

Fry the wings in batches for about 10-12 minutes until golden brown.

Remove wings and let drain on paper towels.

Toss wings in hot sauce if desired.

Serve immediately with your favorite dipping sauces.